原发性干燥综合征分类的EULAR/ACR标准
纳入标准 | 评分* |
|---|---|
唇唾液腺有局灶性淋巴细胞性唾液腺炎且病灶评分† ≥1 | 3 |
抗SSA抗体（抗Ro抗体） | 3 |
至少1只眼染色评分‡ ≥5（或van Bijsterveld评分≥4） | 1 |
至少1只眼Schirmer试验≤5 mm/5 min | 1 |
非刺激性全唾液流速≤0.1 mL/min§ | 1 |
*要符合纳入标准，患者的评分必须≥4，至少有1项眼部或口腔干燥症状，且不符合排除标准。 符合下列排除标准的患者不考虑原发性干燥综合征：
| |
†病灶评分是4mm2 腺体表面中至少存在50个炎性细胞浸润。 | |
‡ As described in Whitcher JP, Shiboski CH, Shiboski SC, et al: A simplified quantitative method for assessing keratoconjunctivitis sicca from the Sjögren's syndrome international registry.Am J Ophthalmol149(3):405–415, 2010.doi: 10.1016/j.ajo.2009.09.013 | |
§ As described in Navazesh M: Methods for collecting saliva.Ann N Y Acad Sci 694:72–77, 1993.doi: 10.1111/j.1749-6632.1993.tb18343.x | |
EULAR/ACR = European League Against Rheumatism/American College of Rheumatology | |
Modified from Shiboski CH, Shiboski SC, Seror R, et al: 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome: A consensus and data-driven methodology involving three international patient cohorts.Arthritis Rheumatol 69(1):35–45, 2017.doi: 10.1002/art.39859 | |