Multiple Organ Dysfunction Score (MODS)

 

Input
 

PaO2		Pascal atm bar cmH2O cmHg ftH2O gm/sqcm inH2O inHg kPa mbar mmHg psi torr
FIO2		%O2 fractionO2 litresO2
Central Venous Pressure		Pascal atm bar cmH2O cmHg ftH2O gm/sqcm inH2O inHg kPa mbar mmHg psi torr
Mean Arterial Pressure		Pascal atm bar cmH2O cmHg ftH2O gm/sqcm inH2O inHg kPa mbar mmHg psi torr
Heart Rate		beats/min
Platelets		#/mcL #/microL /mcL /microL 10E+9/L Mill/mcl Thous/mcL X10E+09/L cells/mcL cells/microL x10(3)/mcL x10(3)/microL x10(6)/L x10(6)/mcL x10(6)/microL x10(9)/L x1000/mm3 x10^3/mcL x10^3/microL x10^6/L x10^6/mcL x10^6/microL x10^9/L
Bilirubin		mcmol/L mg% mg/dL
Creatinine		mcmol/L mg% mg/dL
Glasgow Coma Score		# index none number points score

 

Results
 

PaO2/FIO2		% fraction ratio
Pressure Adjusted Heart Rate		beats/min
MODS Score		# index none number points score
Decimal Precision   0 1 2 3

 

MODS Score

 

0 points:	ICU Mort 0%, Hosp Mort 0%, ICU Stay 2 Days
1 to 4 points:	ICU Mort 1-2%, Hosp Mort 7%, ICU Stay 3 Days
5 to 8 points:	ICU Mort 3-5%, Hosp Mort 16%, ICU Stay 6 Days
9 to 12 points:	ICU Mort 25%, Hosp Mort 50%, ICU Stay 10 Days
13 to 16 points:	ICU Mort 50%, Hosp Mort 70%, ICU Stay 17 Days
17 to 20 points:	ICU Mort 75%, Hosp Mort 82%, ICU Stay 21 Days
21 to 24 points:	ICU Mort 100%, Hosp Mort 100%

 

 

 

 

 
Equations used
 

PaO2/FIO2 = 100 * PaO2 / FIO2

Pressure Adjusted Heart Rate = HeartRate * CentralVenousPressure / MeanArterialPressure

MODSScore = PaO2/FIO2p + plateletsp + bilip + Pressure Adjusted Heart Ratep + renalp + gcsp

 

 

Calculation Details and Variables

• PaO₂/FIO₂p is assigned values by this ordered logic:
  • If PaO₂/FIO₂ >300 PaO₂/FIO₂p = 0
  • Else if PaO₂/FIO₂ ≥226 PaO₂/FIO₂p = 1
  • Else if PaO₂/FIO₂ ≥151 PaO₂/FIO₂p = 2
  • Else if PaO₂/FIO₂ ≥76 PaO₂/FIO₂p = 3
  • Else PaO₂/FIO₂p = 4
• Pressure Adjusted Heart Ratep is assigned values by this ordered logic:
  • If Pressure Adjusted Heart Rate ≤10 Pressure Adjusted Heart Ratep = 0
  • Else if Pressure Adjusted Heart Rate ≤15 Pressure Adjusted Heart Ratep = 1
  • Else if Pressure Adjusted Heart Rate ≤20 Pressure Adjusted Heart Ratep = 2
  • Else if Pressure Adjusted Heart Rate ≤30 Pressure Adjusted Heart Ratep = 3
  • Else Pressure Adjusted Heart Ratep = 4
• plateletsp is assigned values by this ordered logic:
  • If Platelets >120 x10(3)/mcL plateletsp = 0
  • Else if Platelets ≥81 x10(3)/mcL plateletsp = 1
  • Else if Platelets ≥51 x10(3)/mcL plateletsp = 2
  • Else if Platelets ≥21 x10(3)/mcL plateletsp = 3
  • Else plateletsp = 4.
• bilip is assigned values by this ordered logic:
  • If Bilirubin ≤20 mcmol/L bilip = 0
  • Else if Bilirubin <61 mcmol/L bilip = 1
  • Else if Bilirubin <121 mcmol/L bilip = 2
  • Else if Bilirubin ≤240 mcmol/L bilip = 3
  • Else bilip = 4.
• renalp is assigned values by this ordered logic:
  • If Creatinine ≤100 mcmol/L renalp = 0
  • Else if Creatinine <201 mcmol/L renalp = 1
  • Else if Creatinine <351 mcmol/L renalp = 2
  • Else if Creatinine ≤500 mcmol/L renalp = 3
  • Else renalp = 4.
• gcsp is assigned values by this ordered logic:
  • If Glasgow Coma Score >14 points gcsp = 0
  • Else if Glasgow Coma Score >12 points gcsp = 1
  • Else if Glasgow Coma Score >9 points gcsp = 2
  • Else if Glasgow Coma Score >6 points gcsp = 3
  • Else gcsp = 4.

 

References

1. Marshall JC, Cook DJ, Christou NV, et al. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med. 1995 Oct;23(10):1638-52. Review. PubMed ID: 7587228